Chicago White Sox vs Minnesota Twins Picks and Prediction for Saturday, August 29, 2026

The Chicago White Sox visit the Minnesota Twins at Target Field on Saturday, with the first pitch scheduled for 2:10 PM ET. Chicago is 70-63, first in the AL Central with a 2.5-game lead over Cleveland. The White Sox are 3-2 over their last five after Wednesday’s 10-4 win over Texas. Minnesota is 64-70, third in the AL Central, 6.5 games behind Chicago and four games behind Cleveland for the final AL Wild Card spot. The Twins are 1-4 over their last five after Wednesday’s 7-4 loss to the Athletics. Build your bankroll with our free MLB picks.

Chicago White Sox Bring Plenty of Power

Chicago has won three of its last four games, including consecutive victories over Texas by scores of 10-4 and 11-7. The White Sox rank 22nd in MLB batting with a .239 average, but their power numbers stand out. Chicago has hit 178 home runs and scored 641 runs, giving the lineup more scoring production than Minnesota. The White Sox are 29-36 away from home and 29-27 in day games.

Miguel Vargas leads Chicago with 29 home runs and 76 RBIs while batting .251 with a .364 on-base percentage and .497 slugging percentage. Chase Meidroth leads the club with a .273 average and 130 hits, while Colson Montgomery has 27 homers and 73 RBIs. Tristan Peters has also a .282 average, 12 home runs and 52 RBIs. Chicago ranks 16th in MLB pitching with a 4.16 ERA and 1.31 WHIP.

Injuries: Chris Murphy is on the 15-Day IL, Kyle Teel is on the 10-Day IL, and Jordan Leasure and Drew Thorpe are on the 60-Day IL. Andrew Benintendi is on bereavement leave.

Minnesota Twins Try to Stop Recent Slide

Minnesota has dropped four of its last five, including back-to-back road losses against the Athletics. The Twins allowed at least six runs in four of those five games, with their only victory coming 9-6 on Monday. Minnesota has a 35-31 home record and sits six games below .500 overall. The Twins rank 14th in MLB batting with a .245 average, 615 runs, 155 home runs and a .319 on-base percentage.

Josh Bell leads Minnesota with 80 RBIs and 119 hits while batting .253 with 17 home runs. Luke Keaschall has a team-best .269 average and .359 on-base percentage, while Brooks Lee has 21 homers and 70 RBIs. Ryan Jeffers has added a .276 average, 10 home runs and 42 RBIs. Pitching has been Minnesota’s bigger problem, with the Twins ranked 26th in MLB at a 4.69 ERA and 1.39 WHIP.

Injuries: Byron Buxton is day-to-day. Austin Martin is on the 10-Day IL, Joe Ryan is on the 15-Day IL, and Mike Paredes and Mick Abel are on the 60-Day IL.

Pitching Matchup

Chicago White Sox - Erick Fedde

Fedde is 6-8 with a 4.18 ERA and 1.39 WHIP through 118.1 innings. The right-hander has allowed 121 hits and 43 walks while striking out 84. He has surrendered 22 home runs.

Minnesota Twins - Bailey Ober

Ober is 7-4 with a 4.49 ERA and 1.26 WHIP across 108.1 innings. The right-hander has allowed 107 hits, 29 walks and 18 home runs while recording 74 strikeouts.

Chicago White Sox vs Minnesota Twins Game Pick

• Chicago White Sox

Chicago has the better recent form and has already won four of seven meetings against Minnesota this season. The White Sox have scored 23 runs across their last two games and own a 70-63 record, while Minnesota has dropped four of five. Chicago also has 178 home runs compared with Minnesota’s 155, and the Twins rank 26th in MLB pitching with a 4.69 ERA. Fedde’s numbers are not dominant, but Chicago’s recent scoring and power make the White Sox Saturday’s play.

Chicago White Sox vs Minnesota Twins Over/Under Pick

• Over

Recent scoring and pitching numbers point toward runs at Target Field. Chicago has scored 28 runs across its last three games, while Minnesota has allowed at least six runs in four of its last five. Ober owns a 4.49 ERA and has surrendered 18 home runs in 108.1 innings, while Fedde has a 4.18 ERA with 22 homers allowed. Minnesota’s staff ranks 26th in MLB with a 4.69 ERA, and Chicago has hit 178 home runs. The over is the play Saturday.