Arizona Diamondbacks vs. Colorado Rockies, Picks and Prediction, Saturday, May 16, 2026

By: Bosun Akinpelu Published 05/16/2026, 04:10 AM ET
Diamondbacks vs. Rockies prediction
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Arizona (20-22) will be trying to end their road slump when they visit Coors Field on Saturday afternoon to face Colorado (17-27) in the second game of their three-game series at 3:10 PM. ET. Read on to find out which team picks up the win in this Diamondbacks vs. Rockies prediction. Need some winners this baseball season? Check out our Free MLB Picks.

Eduardo Rodriguez, 4-0, 2.25 ERA, will get the start for the Diamondbacks. The Rockies will counter with Tomoyuki Sugano, 3-3, 4.07 ERA.

Arizona is 6-4 in its last 10 games against Colorado.

**This preview was written before Friday’s game was played.**

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Diamondbacks Trying To Bounce Back From Series Loss

The Diamondbacks followed up their series win over the Mets with a series loss to the Rangers. They will try to bounce back from the loss and end their three-series road losing streak when they play the Rockies.

Arizona averages 4.26 runs per game, which is 17th in the league. Their .234 batting average is 20th in the league. Their .299 on base percentage is 27th, while their .387 slugging percentage is 15th.

Ildemaro Vargas has been the most consistent batter for the Diamondbacks. He leads the team with a .331 batting average, seven home runs, and 28 RBI.

Arizona is giving up 4.86 runs per game, which is 23rd in the league. Opponents have a .243 batting average against the Diamondbacks, which is 19th in the league. Their 4.50 ERA is 23rd, while their 1.29 WHIP is 15th.

In his last start, Rodriguez gave up four hits and one run in 8.1 innings, leading to a 5-1 win over the Mets.

Rockies Trying To End Home Slump

The Rockies aren’t playing well at the moment, especially at home, where they’ve lost six of their last seven games. They will try to turn things around and end their home slump when they face the Diamondbacks.

Colorado averages 4.33 runs per game, which is 15th in the league. Their .249 batting average is sixth in the league. Their .317 on base percentage is 20th, while their .401 slugging percentage is eighth.

Troy Johnston leads the Rockies with a .326 batting average, while Mickey Moniak leads the team with 12 home runs and 26 RBI.

Colorado is giving up 5.05 runs per game, which is 27th in the league. Opponents have a .268 batting average against the Rockies, which is 29th in the league. Their 4.77 ERA is also 29th, while their 1.41 WHIP is 24th.

In his last start, Sugano gave up seven hits and five runs in five innings, leading to a 6-0 loss to Philadelphia.

Diamondbacks vs. Rockies Picks

Money Line Pick for Diamondbacks vs. Rockies

  • Arizona Diamondbacks ML (4 Units)

The Diamondbacks have the advantage in this game because they’re playing well offensively and scored nine runs in their last two games. They haven’t been great against right-handers, but the Rockies allow a lot of base hits, and they’re going up against Sugano, who struggled in recent starts, giving up nine runs in his last two starts. With the Rockies also having one of the worst bullpens in the league, they will have a hard time slowing down the Diamondbacks.

Colorado will have a hard time keeping up offensively because they’re not very good against left-handers, and they’re going up against Rodriguez, who has done well on the mound in recent starts, giving up three runs in his last three starts. With Arizona’s bullpen also playing better than Colorado's, expect them to keep the Rockies in check. Take Arizona on the money line.

Over/Under Pick for Diamondbacks vs. Rockies

  • Under (4 Units)

The Diamondbacks average 4.26 runs per game. They’re batting .222 against right-handers, and they’re facing a starter who gave up 10 runs in his last three home starts. The Rockies average 4.33 runs per game. They’re batting .235 against left-handers, and they’re facing a starter who gave up six runs in his last two road starts. Don’t expect these teams to score enough runs to push the score over the total. The Diamondbacks and Rockies played under the total in three of their last four meetings.

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